human APOC4 shRNA silencing AAV

Name
AAV-h-APOC4-shRNA

Cat No
shAAV-201197

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human APOC4.

shAAV-201197

AAV-h-APOC4-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human APOC4 (apolipoprotein C-IV). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

APO-CIV; APOC-IV;

Description (Vector)

APOC4 encodes a lipid-binding protein belonging to the apolipoprotein gene family. The protein is thought to play a role in lipid metabolism. Polymorphisms in this gene may influence circulating lipid levels and may be associated with coronary artery disease risk. APOC4 is present in a cluster with other related apolipoprotein genes on chromosome 19. Naturally occurring read-through transcription exists between this gene and the neighboring downstream apolipoprotein C-II (APOC2) gene.

Gene ID

346

Gene Name (Vector)

apolipoprotein C-IV

Gene Symbol

APOC4

ORF Size (aa)

384

ORF Size (bp)

384 bp

RefSeq ID

NM_001646

RefSeq Synonyms

NM_001646, BC020723,

Species

human

UniGene ID

Hs.655423

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.