human APOB48R shRNA silencing AAV

Name 
AAV-h-APOB48R-shRNA
Cat No 
shAAV-201175
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human APOBR.

shAAV-201175
AAV-h-APOB48R-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human APOBR (apolipoprotein B receptor). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
APOB100R; APOB48R
Description (Vector)
Apolipoprotein B48 receptor is a macrophage receptor that binds to the apolipoprotein B48 of dietary triglyceride (TG)-rich lipoproteins. This receptor may provide essential lipids, lipid-soluble vitamins and other nutrients to reticuloendothelial cells. If overwhelmed with elevated plasma triglyceride, the apolipoprotein B48 receptor may contribute to foam cell formation, endothelial dysfunction, and atherothrombogenesis.
Gene ID
55911
Gene Name (Vector)
apolipoprotein B receptor
Gene Symbol
APOBR
HGNC ID
HGNC:24087
ORF Size (aa)
3267
ORF Size (bp)
3267 bp
RefSeq ID
NM_018690
RefSeq Synonyms
NM_018690, BC119788, BC119786,
Species
human
UniGene ID
Hs.200333

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.