human AP1B1 shRNA silencing AAV

Name
AAV-h-AP1B1-shRNA

Cat No
shAAV-201073

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human AP1B1.

shAAV-201073

AAV-h-AP1B1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human AP1B1 (adaptor related protein complex 1 beta 1 subunit). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

ADTB1; AP105A; BAM22; CLAPB2

Description (Vector)

Adaptor protein complex 1 is found at the cytoplasmic face of coated vesicles located at the Golgi complex, where it mediates both the recruitment of clathrin to the membrane and the recognition of sorting signals within the cytosolic tails of transmembrane receptors. This complex is a heterotetramer composed of two large, one medium, and one small adaptin subunit. The protein encoded by this gene serves as one of the large subunits of this complex and is a member of the adaptin protein family. This gene is a candidate meningioma gene. Alternative splicing results in multiple transcript variants.

Gene ID

162

Gene Name (Vector)

adaptor related protein complex 1 beta 1 subunit

Gene Symbol

AP1B1

HGNC ID

HGNC:554

ORF Size (aa)

2760

ORF Size (bp)

2760 bp

RefSeq ID

NM_001127

RefSeq Synonyms

NM_145730, NM_001166019, NM_001127, BC046242,

Species

human

UniGene ID

Hs.368794

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.