human ANKRD26 shRNA silencing AAV

Name 
AAV-h-ANKRD26-shRNA
Cat No 
shAAV-200962
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human ANKRD26.

shAAV-200962
AAV-h-ANKRD26-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human ANKRD26 (ankyrin repeat domain 26). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ankyrin repeat domain-containing protein 26; bA145E8.1; GNS/ANKRD26/NCKAP1L fusion; THC2
Description (eCommerce)
The ANKRD26 (ankyrin repeat domain 26) gene has been implicated to give rise to the POTE gene family which encode proteins containing ankyrin repeats and coiled –coil domains. The generation of mice that bear mutant AKFRD26 indicates that ANKRD26 plays a role in obesity, insulin resistance, and body size.
Description (Vector)
ANKRD26 encodes a protein containing N-terminal ankyrin repeats which function in protein-protein interactions. Mutations in this gene are associated with autosomal dominant thrombocytopenia-2. Pseudogenes of this gene are found on chromosome 7, 10, 13 and 16. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene ID
22852
Gene Name (eCommerce)
ankyrin repeat domain 26
Gene Name (Vector)
ankyrin repeat domain 26
Gene Symbol
ANKRD26
HGNC ID
HGNC:29186
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
5181
ORF Size (bp)
5181 bp
Protein Name (eCommerce)
Ankyrin repeat domain-containing protein 26
RefSeq ID
NM_014915
RefSeq Synonyms
NM_014915, NM_001256053, BC130453,
Research Areas
Metabolism/Metabolic Process,Signal Transduction
Research Areas (Faceted)
cell_biology,metabolism,signal_transduction
Species
human
Target Sentence
The ANKRD26 (ankyrin repeat domain 26) gene has been implicated to give rise to the POTE gene family which encode proteins containing ankyrin repeats and coiled –coil domains. The generation of mice that bear mutant AKFRD26 indicates that ANKRD26 plays a role in obesity, insulin resistance, and body size.
UniGene ID
Hs.361041
UniProt ID (eCommerce)
Q9UPS8

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.