human ANKH shRNA silencing AAV

Name 
AAV-h-ANKH-shRNA
Cat No 
shAAV-200930
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human ANKH.

shAAV-200930
AAV-h-ANKH-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human ANKH (ANKH inorganic pyrophosphate transport regulator). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ANK; CCAL2; CMDJ; CPPDD; HANK; MANK
Description (Vector)
ANKH encodes a multipass transmembrane protein that is expressed in joints and other tissues and controls pyrophosphate levels in cultured cells. Progressive ankylosis-mediated control of pyrophosphate levels has been suggested as a possible mechanism regulating tissue calcification and susceptibility to arthritis in higher animals. Mutations in this gene have been associated with autosomal dominant craniometaphyseal dysplasia.
Gene ID
56172
Gene Name (Vector)
ANKH inorganic pyrophosphate transport regulator
Gene Symbol
ANKH
HGNC ID
HGNC:15492
ORF Size (aa)
1479
ORF Size (bp)
1479 bp
RefSeq ID
NM_054027
RefSeq Synonyms
NM_054027, BC014526, BC009835,
Species
human
UniGene ID
Hs.156727

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.