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human CTPS Over-expression AAV

Name 
AAV-h-CTPS
Cat No 
AAV-206255
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human CTPS1.

AAV-206255
AAV-h-CTPS

Ready-to-use AAV expressing Human CTPS1 (CTP synthase 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CTP synthase 1; CTP synthetase 1; CTPS; cytidine 5-prime triphosphate synthetase; cytidine 5'-triphosphate synthetase; GATD5; IMD24; UTP--ammonia ligase 1
Description (eCommerce)
CTP synthase 1 (CTPS1) catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P17812].
Description (Vector)
The catalytic conversion of UTP to CTP is accomplished by the enzyme cytidine-5-prime-triphosphate synthetase. The enzyme is important in the biosynthesis of phospholipids and nucleic acids, and plays a key role in cell growth, development, and tumorigenesis. The region to which the CTPS gene has been mapped is the location of breakpoints involved in several tumor types
Gene ID
1503
Gene Name (eCommerce)
CTP synthase 1
Gene Name (Vector)
CTP synthase 1
Gene Symbol
CTPS1
HGNC ID
HGNC:2519
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1776
ORF Size (bp)
1776 bp
Protein Name (eCommerce)
CTP synthase 1
RefSeq ID
NM_001905
RefSeq Synonyms
NM_001905, NM_001301237, BC009408,
Research Areas
Metabolism/Metabolic Process
Research Areas (Faceted)
cell_biology,metabolism
Species
human
Target Sentence
CTP synthase 1 (CTPS1) catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P17812].
UniGene ID
Hs.473087
UniProt ID (eCommerce)
P17812

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.