human AMMECR1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human AMMECR1.
shAAV-200859
AAV-h-AMMECR1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human AMMECR1 (Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AMMERC1
Description (Vector)
The exact function of this gene is not known, however, submicroscopic deletion of the X chromosome including this gene, COL4A5, and FACL4 genes, result in a contiguous gene deletion syndrome, the AMME complex (Alport syndrome, mental retardation, midface hypoplasia, and elliptocytosis). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Gene ID
9949
Gene Name (Vector)
Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
Gene Symbol
AMMECR1
HGNC ID
HGNC:467
ORF Size (aa)
891
RefSeq ID
NM_015365
RefSeq Synonyms
NM_015365, NM_001171689, NM_001025580, BC060813,
Species
human
UniGene ID
Hs.656243
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.