human AMHR2 shRNA silencing AAV

Name 
AAV-h-AMHR2-shRNA
Cat No 
shAAV-200846
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human AMHR2.

shAAV-200846
AAV-h-AMHR2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human AMHR2 (anti-Mullerian hormone receptor type 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AMHR; MISR2; MISRII; MRII
Description (Vector)
AMHR2 encodes the receptor for the anti-Mullerian hormone (AMH) which, in addition to testosterone, results in male sex differentiation. AMH and testosterone are produced in the testes by different cells and have different effects. Testosterone promotes the development of male genitalia while the binding of AMH to the encoded receptor prevents the development of the mullerian ducts into uterus and Fallopian tubes. Mutations in this gene are associated with persistent Mullerian duct syndrome type II. Alternatively spliced transcript variants encoding different isoforms have been identified.
Gene ID
269
Gene Name (Vector)
anti-Mullerian hormone receptor type 2
Gene Symbol
AMHR2
HGNC ID
HGNC:465
ORF Size (aa)
1722
ORF Size (bp)
1722 bp
RefSeq ID
NM_020547
RefSeq Synonyms
NM_020547, NM_001164691, NM_001164690, BC136356, BC126316,
Species
human
UniGene ID
Hs.659889

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.