human AMBP shRNA silencing AAV

Name
AAV-h-AMBP-shRNA

Cat No
shAAV-200835

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human AMBP.

shAAV-200835

AAV-h-AMBP-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human AMBP (alpha-1-microglobulin/bikunin precursor). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

A1M; EDC1; HCP; HI30; IATIL; ITI; ITIL; ITILC; UTI

Description (Vector)

AMBP encodes a complex glycoprotein secreted in plasma. The precursor is proteolytically processed into distinct functioning proteins: alpha-1-microglobulin, which belongs to the superfamily of lipocalin transport proteins and may play a role in the regulation of inflammatory processes, and bikunin, which is a urinary trypsin inhibitor belonging to the superfamily of Kunitz-type protease inhibitors and plays an important role in many physiological and pathological processes. AMBP is located on chromosome 9 in a cluster of lipocalin genes.

Gene ID

259

Gene Name (Vector)

alpha-1-microglobulin/bikunin precursor

Gene Symbol

AMBP

HGNC ID

HGNC:453

ORF Size (aa)

1059

ORF Size (bp)

1059 bp

RefSeq ID

NM_001633

RefSeq Synonyms

NM_001633, BC041593,

Species

human

UniGene ID

Hs.436911

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.