human ALKBH2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human ALKBH2.
shAAV-200786
AAV-h-ALKBH2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human ALKBH2 (alkB homolog 2, alpha-ketoglutarate dependent dioxygenase). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ABH2
Description (Vector)
The Escherichia coli AlkB protein protects against the cytotoxicity of methylating agents by repair of the specific DNA lesions generated in single-stranded DNA. ALKBH2 and ALKBH3 (MIM 610603) are E. coli AlkB homologs that catalyze the removal of 1-methyladenine and 3-methylcytosine (Duncan et al., 2002 (PubMed 12486230)).(supplied by OMIM, Mar 2008)
Gene ID
121642
Gene Name (Vector)
alkB homolog 2, alpha-ketoglutarate dependent dioxygenase
Gene Symbol
ALKBH2
HGNC ID
HGNC:32487
ORF Size (aa)
786
RefSeq ID
NM_001001655
RefSeq Synonyms
NM_001205180, NM_001205179, NM_001145375, NM_001145374, NM_001001655, BC070489,
Species
human
UniGene ID
Hs.374458
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.