human ALG2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human ALG2.
shAAV-200777
AAV-h-ALG2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human ALG2 (ALG2, alpha-1,3/1,6-mannosyltransferase). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CDGIi; CMS14; CMSTA3; hALPG2; NET38
Description (Vector)
ALG2 encodes a member of the glycosyltransferase 1 family. The encoded protein acts as an alpha 1,3 mannosyltransferase, mannosylating Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate. Defects in this gene have been associated with congenital disorder of glycosylation type Ih (CDG-Ii). Alternative splicing results in multiple transcript variants.
Gene ID
85365
Gene Name (Vector)
ALG2, alpha-1,3/1,6-mannosyltransferase
Gene Symbol
ALG2
HGNC ID
HGNC:23159
ORF Size (aa)
1251
ORF Size (bp)
1251 bp
RefSeq ID
NM_033087
RefSeq Synonyms
NM_033087, BC017876, BC015126,
Species
human
UniGene ID
Hs.40919
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.