human ALDH6A1 shRNA silencing AAV

Name
AAV-h-ALDH6A1-shRNA

Cat No
shAAV-200744

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human ALDH6A1.

shAAV-200744

AAV-h-ALDH6A1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human ALDH6A1 (aldehyde dehydrogenase 6 family member A1). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

MMSADHA; MMSDH

Description (Vector)

This protein belongs to the aldehyde dehydrogenases family of proteins. This enzyme plays a role in the valine and pyrimidine catabolic pathways. The product of this gene, a mitochondrial methylmalonate semialdehyde dehydrogenase, catalyzes the irreversible oxidative decarboxylation of malonate and methylmalonate semialdehydes to acetyl- and propionyl-CoA. Methylmalonate semialdehyde dehydrogenase deficiency is characterized by elevated beta-alanine, 3-hydroxypropionic acid, and both isomers of 3-amino and 3-hydroxyisobutyric acids in urine organic acids.

Gene ID

4329

Gene Name (Vector)

aldehyde dehydrogenase 6 family member A1

Gene Symbol

ALDH6A1

HGNC ID

HGNC:7179

ORF Size (aa)

1608

ORF Size (bp)

1608 bp

RefSeq ID

NM_005589

RefSeq Synonyms

NM_005589, NM_001278594, NM_001278593, BC032371, BC004909,

Species

human

UniGene ID

Hs.293970

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.