human ALDH5A1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human ALDH5A1.
shAAV-200743
AAV-h-ALDH5A1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human ALDH5A1 (aldehyde dehydrogenase 5 family member A1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
SSADH; SSDH
Description (Vector)
This protein belongs to the aldehyde dehydrogenase family of proteins. This gene encodes a mitochondrial NAD(+)-dependent succinic semialdehyde dehydrogenase. A deficiency of this enzyme, known as 4-hydroxybutyricaciduria, is a rare inborn error in the metabolism of the neurotransmitter 4-aminobutyric acid (GABA). In response to the defect, physiologic fluids from patients accumulate GHB, a compound with numerous neuromodulatory properties. Two transcript variants encoding distinct isoforms have been identified for this gene.
Gene ID
7915
Gene Name (Vector)
aldehyde dehydrogenase 5 family member A1
Gene Symbol
ALDH5A1
HGNC ID
HGNC:408
ORF Size (aa)
1608
ORF Size (bp)
1608 bp
RefSeq ID
NM_170740
RefSeq Synonyms
NM_170740, NM_001080, BC034321,
Species
human
UniGene ID
Hs.371723
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.