human AFF2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human AFF2.
shAAV-200533
AAV-h-AFF2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human AFF2 (AF4/FMR2 family member 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
FMR2; FMR2P; FRAXE; MRX2; OX19
Description (Vector)
AFF2 encodes a putative transcriptional activator that is a member of the AF4\FMR2 gene family. AFF2 is associated with the folate-sensitive fragile X E locus on chromosome X. A repeat polymorphism in the fragile X E locus results in silencing of this gene causing Fragile X E syndrome. Fragile X E syndrome is a form of nonsyndromic X-linked mental retardation. Alternate splicing results in multiple transcript variants.
Gene ID
2334
Gene Name (Vector)
AF4/FMR2 family member 2
Gene Symbol
AFF2
HGNC ID
HGNC:3776
ORF Size (aa)
3906
ORF Size (bp)
3906 bp
RefSeq ID
NM_002025
RefSeq Synonyms
NM_002025, NM_001170628, NM_001169125, NM_001169124, NM_001169123, NM_001169122, BC143744, BC143740, BC132683,
Species
human
UniGene ID
Hs.496911
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.