human ADRA1A shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human ADRA1A.
shAAV-200498
AAV-h-ADRA1A-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human ADRA1A (adrenoceptor alpha 1A). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ADRA1C; ADRA1L1; ALPHA1AAR
Description (Vector)
Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1A-adrenergic receptor. Alternative splicing of this gene generates four transcript variants, which encode four different isoforms with distinct C-termini but having similar ligand binding properties.
Gene ID
148
Gene Name (Vector)
adrenoceptor alpha 1A
Gene Symbol
ADRA1A
HGNC ID
HGNC:277
ORF Size (aa)
1401
ORF Size (bp)
1401 bp
RefSeq ID
NM_033303
RefSeq Synonyms
NM_033304, NM_033303, NM_033302, NM_001322504, NM_001322503, NM_001322502, NM_000680, BC095512,
Species
human
UniGene ID
Hs.709175
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.