human ADCY8 shRNA silencing AAV

Name 
AAV-h-ADCY8-shRNA
Cat No 
shAAV-200430
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human ADCY8.

shAAV-200430
AAV-h-ADCY8-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human ADCY8 (adenylate cyclase 8). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AC8; ADCY3; HBAC1
Description (Vector)
Adenylate cyclase is a membrane bound enzyme that catalyses the formation of cyclic AMP from ATP. The enzymatic activity is under the control of several hormones, and different polypeptides participate in the transduction of the signal from the receptor to the catalytic moiety. Stimulatory or inhibitory receptors (Rs and Ri) interact with G proteins (Gs and Gi) that exhibit GTPase activity and they modulate the activity of the catalytic subunit of the adenylyl cyclase
Gene ID
114
Gene Name (Vector)
adenylate cyclase 8
Gene Symbol
ADCY8
HGNC ID
HGNC:239
ORF Size (aa)
3753
ORF Size (bp)
3753 bp
RefSeq ID
NM_001115
RefSeq Synonyms
NM_001115, BC111456,
Species
human
UniGene ID
Hs.591859

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.