human ADAM28 shRNA silencing AAV

Name
AAV-h-ADAM28-shRNA

Cat No
shAAV-200359

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human ADAM28.

shAAV-200359

AAV-h-ADAM28-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human ADAM28 (ADAM metallopeptidase domain 28). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

ADAM 28; eMDC II; eMDCII; MDC-L; MDCL

Description (Vector)

ADAM28 encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene is a lymphocyte-expressed ADAM protein. Alternative splicing results in two transcript variants. The shorter version encodes a secreted isoform, while the longer version encodes a transmembrane isoform.

Gene ID

10863

Gene Name (Vector)

ADAM metallopeptidase domain 28

Gene Symbol

ADAM28

HGNC ID

HGNC:206

ORF Size (aa)

2328

ORF Size (bp)

2328 bp

RefSeq ID

NM_014265

RefSeq Synonyms

NM_021777, NM_014265, NM_001304351, BC136478,

Species

human

UniGene ID

Hs.174030

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.