human ADAM19 shRNA silencing AAV

Name
AAV-h-ADAM19-shRNA

Cat No
shAAV-200351

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human ADAM19.

shAAV-200351

AAV-h-ADAM19-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human ADAM19 (ADAM metallopeptidase domain 19). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

FKSG34; MADDAM; MLTNB

Description (Vector)

ADAM19 encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This member is a type I transmembrane protein and serves as a marker for dendritic cell differentiation. It has also been demonstrated to be an active metalloproteinase, which may be involved in normal physiological and pathological processes such as cells migration, cell adhesion, cell-cell and cell-matrix interactions, and signal transduction.

Gene ID

8728

Gene Name (Vector)

ADAM metallopeptidase domain 19

Gene Symbol

ADAM19

HGNC ID

HGNC:197

ORF Size (aa)

2868

ORF Size (bp)

2868 bp

RefSeq ID

NM_033274

RefSeq Synonyms

NM_033274, BC140323,

Species

human

UniGene ID

Hs.483944

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.