human ADAM10 shRNA silencing AAV

Name 
AAV-h-ADAM10-shRNA
Cat No 
shAAV-200345
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human ADAM10.

shAAV-200345
AAV-h-ADAM10-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human ADAM10 (ADAM metallopeptidase domain 10). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AD10; AD18; CD156c; CDw156; HsT18717; kuz; MADM; RAK
Description (Vector)
Members of the ADAM family are cell surface proteins with a unique structure possessing both potential adhesion and protease domains. This gene encodes and ADAM family member that cleaves many proteins including TNF-alpha and E-cadherin.
Gene ID
102
Gene Name (Vector)
ADAM metallopeptidase domain 10
Gene Symbol
ADAM10
HGNC ID
HGNC:188
ORF Size (aa)
1539
ORF Size (bp)
1539 bp
RefSeq ID
NM_001110
RefSeq Synonyms
NM_001320570, NM_001110, BC126253,
Species
human
UniGene ID
Hs.578508

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.