human ACSF3 shRNA silencing AAV

Name 
AAV-h-ACSF3-shRNA
Cat No 
shAAV-200248
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human ACSF3.

shAAV-200248
AAV-h-ACSF3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human ACSF3 (acyl-CoA synthetase family member 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Description (Vector)
ACSF3 encodes a member of the acyl-CoA synthetase family of enzymes that activate fatty acids by catalyzing the formation of a thioester linkage between fatty acids and coenzyme A. The encoded protein is localized to mitochondria, has high specificity for malonate and methylmalonate and possesses malonyl-CoA synthetase activity. Mutations in this gene are a cause of combined malonic and methylmalonic aciduria. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Gene ID
197322
Gene Name (Vector)
acyl-CoA synthetase family member 3
Gene Symbol
ACSF3
HGNC ID
HGNC:27288
ORF Size (aa)
1731
ORF Size (bp)
1731 bp
RefSeq ID
NM_174917
RefSeq Synonyms
NM_174917, NM_001284316, NM_001243279, NM_001127214, BC072391, BC028399,
Species
human
UniGene ID
Hs.461727

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.