human ACADL shRNA silencing AAV

Name
AAV-h-ACADL-shRNA

Cat No
shAAV-200154

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human ACADL.

shAAV-200154

AAV-h-ACADL-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human ACADL (acyl-CoA dehydrogenase, long chain). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

ACAD4; LCAD

Description (Vector)

ACADL belongs to the acyl-CoA dehydrogenase family, which is a family of mitochondrial flavoenzymes involved in fatty acid and branched chain amino-acid metabolism. This protein is one of the four enzymes that catalyze the initial step of mitochondrial beta-oxidation of straight-chain fatty acid. Defects in this gene are the cause of long-chain acyl-CoA dehydrogenase (LCAD) deficiency, leading to nonketotic hypoglycemia.

Gene ID

Gene Name (Vector)

acyl-CoA dehydrogenase, long chain

Gene Symbol

ACADL

HGNC ID

HGNC:88

ORF Size (aa)

1293

ORF Size (bp)

1293 bp

RefSeq ID

NM_001608

RefSeq Synonyms

NM_001608, BC064549, BC039063,

Species

human

UniGene ID

Hs.471277

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.