human ACAA1 shRNA silencing AAV

Name 
AAV-h-ACAA1-shRNA
Cat No 
shAAV-200144
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human ACAA1.

shAAV-200144
AAV-h-ACAA1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human ACAA1 (acetyl-CoA acyltransferase 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
3-ketoacyl-CoA thiolase, peroxisomal; ACAA; Acetyl-CoA acyltransferase; acetyl-Coenzyme A acyltransferase 1; beta-ketothiolase; epididymis secretory sperm binding protein; peroxisomal 3-oxoacyl-CoA thiolase; peroxisomal 3-oxoacyl-Coenzyme A thiolase; PTHIO; testicular tissue protein Li 197; THIO
Description (eCommerce)
Peroxisomal 3-oxoacyl-CoA thiolase (ACAA1) is an enzyme operative in the beta-oxidation system of the peroxisomes. Deficiency of this enzyme leads to pseudo-Zellweger syndrome [taken from NCBI Entrez Gene (Gene ID: 30)].
Description (Vector)
ACAA1 encodes an enzyme operative in the beta-oxidation system of the peroxisomes. Deficiency of this enzyme leads to pseudo-Zellweger syndrome. Alternative splicing results in multiple transcript variants.
Gene ID
30
Gene Name (eCommerce)
acetyl-CoA acyltransferase 1
Gene Name (Vector)
acetyl-CoA acyltransferase 1
Gene Symbol
ACAA1
HGNC ID
HGNC:82
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
996
ORF Size (bp)
996 bp
Protein Name (eCommerce)
3-ketoacyl-CoA thiolase, peroxisomal
RefSeq ID
NM_001607
RefSeq Synonyms
NM_001607, NM_001130410, BC014474, BC011977, BC000635,
Research Areas
Acyltransferase,Metabolism/Metabolic Process,Signal Transduction
Research Areas (Faceted)
signal_transduction,cell_biology,metabolism
Species
human
Target Sentence
Peroxisomal 3-oxoacyl-CoA thiolase (ACAA1) is an enzyme operative in the beta-oxidation system of the peroxisomes. Deficiency of this enzyme leads to pseudo-Zellweger syndrome [taken from NCBI Entrez Gene (Gene ID: 30)].
UniGene ID
Hs.643487
UniProt ID (eCommerce)
P09110

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.