human ABI3 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human ABI3.
shAAV-200125
AAV-h-ABI3-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human ABI3 (ABI family member 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
NESH; SSH3BP3
Description (Vector)
ABI3 encodes a member of an adaptor protein family. Members of this family encode proteins containing a homeobox homology domain, proline rich region and Src-homology 3 (SH3) domain, and are components of the Abi/WAVE complex which regulates Rac-dependent actin polymerization. The encoded protein inhibits ectopic metastasis of tumor cells as well as cell migration. This may be accomplished through interaction with p21-activated kinase.
Gene ID
51225
Gene Name (Vector)
ABI family member 3
Gene Symbol
ABI3
HGNC ID
HGNC:29859
ORF Size (aa)
1101
ORF Size (bp)
1101 bp
RefSeq ID
NM_016428
RefSeq Synonyms
NM_016428, NM_001135186, BC007780,
Species
human
UniGene ID
Hs.130719
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.