human ABI2 shRNA silencing AAV

Name 
AAV-h-ABI2-shRNA
Cat No 
shAAV-200124
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human ABI2.

shAAV-200124
AAV-h-ABI2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human ABI2 (abl interactor 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
abelson interactor 2; ABI-2; ABI2B; abl binding protein 3; abl interactor 2; Abl-binding protein 3; AblBP3; abl-interacting protein 1 (SH3-containing protein); abl-interactor protein 2b; AIP1; AIP-1; arg protein tyrosine kinase-binding protein; arg-binding protein 1; argBP1; argBPIA; argBPIB; SSH3BP2
Description (eCommerce)
Abelson interactor 2 (Abi-2) may act in the regulation of cell growth and transformation by interacting with nonreceptor tyrosine kinases ABL1 and/or ABL2. Abi-2 regulates ABL1/c-Abl-mediated phosphorylation of MENA, and may be involved in cytoskeletal reorganization [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9NYB9].
Gene ID
10152
Gene Name (eCommerce)
abl interactor 2
Gene Name (Vector)
abl interactor 2
Gene Symbol
ABI2
HGNC ID
HGNC:24011
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1428
ORF Size (bp)
1428 bp
Protein Name (eCommerce)
Abl interactor 2
RefSeq ID
NM_005759
RefSeq Synonyms
NM_005759, NM_001282932, NM_001282927, NM_001282926, NM_001282925, BC001439,
Research Areas
Cytoskeleton,Immunology,Innate Immunity,RAC1 Signaling,Signal Transduction
Research Areas (Faceted)
cell_biology,immunology,signal_transduction
Species
human
Target Sentence
Abelson interactor 2 (Abi-2) may act in the regulation of cell growth and transformation by interacting with nonreceptor tyrosine kinases ABL1 and/or ABL2. Abi-2 regulates ABL1/c-Abl-mediated phosphorylation of MENA, and may be involved in cytoskeletal reorganization [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9NYB9].
UniGene ID
Hs.471156
UniProt ID (eCommerce)
Q9NYB9

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.