rat FNTA shRNA silencing Adenovirus

Name
Ad-r-FNTA-shRNA

Cat No
shADV-292163

Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Rat Fnta.

shADV-292163

Ad-r-FNTA-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Rat Fnta (farnesyltransferase, CAAX box, alpha). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

shRNA Validated

Yes

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

PFAS

Description (Vector)

Catalyzes the transfer of a farnesyl or geranyl-geranyl moiety from farnesyl or geranyl-geranyl pyrophosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. The alpha subunit is thought to participate in a stable complex with the substrate. The beta subunit binds the peptide substrate. Through RAC1 prenylation and activation may positively regulate neuromuscular junction development downstream of MUSK (By similarity).

Gene ID

25318

Gene Name (Vector)

farnesyltransferase, CAAX box, alpha

Gene Symbol

Fnta

ORF Size (aa)

1134

ORF Size (bp)

1134 bp

RefSeq ID

NM_012847

RefSeq Synonyms

NM_012847, BC085758,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.