mouse RACGAP1 shRNA silencing Adenovirus

Name 
Ad-m-RACGAP1-shRNA
Cat No 
shADV-270050
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Mouse Racgap1.

shADV-270050
Ad-m-RACGAP1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Racgap1 (Rac GTPase-activating protein 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
AI227039; AI327394; Band25; gtl11; GTPase; MgcRacGAP; mKIAA1478
Description (Vector)
Component of the centralspindlin complex that serves as a microtubule-dependent and Rho-mediated signaling required for the myosin contractile ring formation during the cell cycle cytokinesis. Plays key roles in controlling cell growth and differentiation of hematopoietic cells through mechanisms other than regulating Rac GTPase activity. Also involved in the regulation of growth-related processes in adipocytes and myoblasts. May be involved in regulating spermatogenesis and in the RACGAP1 pathway in neuronal proliferation. Shows strong GAP (GTPase activation) activity towards CDC42 and RAC1 and less towards RHOA. Essential for the early stages of embryogenesis. May play a role in regulating cortical activity through RHOA during cytokinesis. May participate in the regulation of sulfate transport in male germ cells.
Gene ID
26934
Gene Name (Vector)
Rac GTPase-activating protein 1
Gene Symbol
Racgap1
ORF Size (aa)
1887
ORF Size (bp)
1887 bp
RefSeq ID
NM_012025
RefSeq Synonyms
NM_012025, NM_001253809, NM_001253808, BC010715,
Species
mouse
UniGene ID
Mm.273804

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.