mouse ERCC2 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Ercc2.
shADV-258632
Ad-m-ERCC2-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Ercc2 (excision repair cross-complementing rodent repair deficiency, complementation group 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AA407812; AU020867; AW240756; CXPD; Ercc-2; Mhdarco15; RCO015; XPD
Description (Vector)
ATP-dependent 5'-3' DNA helicase, component of the core-TFIIH basal transcription factor. Involved in nucleotide excision repair (NER) of DNA by opening DNA around the damage, and in RNA transcription by RNA polymerase II by anchoring the CDK-activating kinase (CAK) complex, composed of CDK7, cyclin H and MAT1, to the core-TFIIH complex. Involved in the regulation of vitamin-D receptor activity. As part of the mitotic spindle-associated MMXD complex it plays a role in chromosome segregation. Might have a role in aging process and could play a causative role in the generation of skin cancers.
Gene ID
13871
Gene Name (Vector)
excision repair cross-complementing rodent repair deficiency, complementation group 2
Gene Symbol
Ercc2
ORF Size (aa)
2220
ORF Size (bp)
2220 bp
RefSeq ID
NM_007949
RefSeq Synonyms
NM_007949, BC034517,
Species
mouse
UniGene ID
Mm.36524
Recently Viewed Products
AAV-h-RBBP4-shRNA
Cat No: shAAV-220824
Ad-h-RBBP4-shRNA
Cat No: shADV-220824
AAV-h-FOXA3
Cat No: AAV-209227
Ad-h-NOSTRIN
Cat No: ADV-216912
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.