mouse EFNA3 shRNA silencing Adenovirus

Name
Ad-m-EFNA3-shRNA

Cat No
shADV-257814

Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Mouse Efna3.

shADV-257814

Ad-m-EFNA3-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Efna3 (ephrin A3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

shRNA Validated

Yes

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

AW494418; EFL-2; Ehk1-L; Epl3; LERK-3

Description (Vector)

Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling (By similarity).

Gene ID

13638

Gene Name (Vector)

ephrin A3

Gene Symbol

Efna3

ORF Size (aa)

693

ORF Size (bp)

693 bp

RefSeq ID

NM_010108

RefSeq Synonyms

NM_010108, BC125003, BC107002,

Species

mouse

UniGene ID

Mm.331159

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.