human RUVBL2 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human RUVBL2.
shADV-222125
Ad-h-RUVBL2-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human RUVBL2 (RuvB like AAA ATPase 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
48 kDa TATA box-binding protein-interacting protein; 48 kDa TBP-interacting protein; 51 kDa erythrocyte cytosolic protein; CGI-46; ECP51; ECP-51; erythrocyte cytosolic protein, 51-KD; INO80 complex subunit J; INO80J; repressing pontin 52; REPTIN; Reptin 52; reptin52 protein; RuvB (E coli homolog)-like 2; ruvB-like 2; RVB2; TAP54-beta; TIH2; TIP48; TIP49B; TIP60-associated protein 54-beta
Description (eCommerce)
RuvB-like 2 (RuvBL2) is the second human homologue of the bacterial RuvB gene. Bacterial RuvB protein is a DNA helicase essential for homologous recombination and DNA double-strand break repair. Functional analysis showed that this protein has both ATPase and DNA helicase activities [taken from NCBI Entrez Gene (GeneID: 9400)].
Description (Vector)
RUVBL2 encodes the second human homologue of the bacterial RuvB gene. Bacterial RuvB protein is a DNA helicase essential for homologous recombination and DNA double-strand break repair. Functional analysis showed that this gene product has both ATPase and DNA helicase activities. RUVBL2 is physically linked to the CGB/LHB gene cluster on chromosome 19q13.3, and is very close (55 nt) to the LHB gene, in the opposite orientation.
Gene ID
10856
Gene Name (eCommerce)
RuvB like AAA ATPase 2
Gene Name (Vector)
RuvB like AAA ATPase 2
Gene Symbol
RUVBL2
HGNC ID
HGNC:10475
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1392
ORF Size (bp)
1392 bp
Protein Name (eCommerce)
RuvB-like 2
RefSeq ID
NM_006666
RefSeq Synonyms
NM_006666, NM_001321191, NM_001321190, BC008355, BC004531, BC000428,
Research Areas
Cell Cycle,DNA Damage/Repair,Helicase Activity,Histone Modification,Protein Folding,Signal Transduction,Telomeric Maintenance,Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,cell_cycle,genetics,transcription_translation,signal_transduction
Species
human
Target Sentence
RuvB-like 2 (RuvBL2) is the second human homologue of the bacterial RuvB gene. Bacterial RuvB protein is a DNA helicase essential for homologous recombination and DNA double-strand break repair. Functional analysis showed that this protein has both ATPase and DNA helicase activities [taken from NCBI Entrez Gene (GeneID: 9400)].
UniGene ID
Hs.515846
UniProt ID (eCommerce)
Q9Y230
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.