human RNF2 shRNA silencing Adenovirus

Name 
Ad-h-RNF2-shRNA
Cat No 
shADV-221397
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human RNF2.

shADV-221397
Ad-h-RNF2-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human RNF2 (ring finger protein 2). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
BAP1; BAP-1; DING; E3 ubiquitin-protein ligase RING2; HIP2-interacting protein 3; HIPI3; huntingtin-interacting protein 2-interacting protein 3; protein DinG; RING finger protein 1B; RING finger protein 2; RING finger protein BAP-1; RING1B; RING2; RING-type E3 ubiquitin transferase RING2
Description (eCommerce)
Ring finger protein 2 (RNF2) is a polycomb group (PcG) protein. RNF2 has been shown to interact with, and suppress the activity of, transcription factor CP2 (TFCP2/CP2). Studies of the mouse counterpart suggest the involvement of this gene in the specification of anterior-posterior axis, as well as in cell proliferation in early development. This protein has also been found to interact with huntingtin interacting protein 2 (HIP2), an ubiquitin-conjugating enzyme, and possess ubiquitin ligase activity [taken from NCBI Entrez Gene (Gene ID: 6045)].
Description (Vector)
Polycomb group (PcG) of proteins form the multiprotein complexes that are important for the transcription repression of various genes involved in development and cell proliferation. The protein encoded by this gene is one of the PcG proteins. It has been shown to interact with, and suppress the activity of, transcription factor CP2 (TFCP2/CP2). Studies of the mouse counterpart suggested the involvement of this gene in the specification of anterior-posterior axis, as well as in cell proliferation in early development. This protein was also found to interact with huntingtin interacting protein 2 (HIP2), an ubiquitin-conjugating enzyme, and possess ubiquitin ligase activity.
Gene ID
6045
Gene Name (eCommerce)
ring finger protein 2
Gene Name (Vector)
ring finger protein 2
Gene Symbol
RNF2
HGNC ID
HGNC:10061
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1011
ORF Size (bp)
1011 bp
Protein Name (eCommerce)
E3 ubiquitin-protein ligase RING2
RefSeq ID
NM_007212
RefSeq Synonyms
NM_007212, BC012583,
Research Areas
Cell Cycle,Chromatin Remodeling,Complexome,Histone Modification,Polycomb Proteins,Transcription Factor/Regulator,Ubiquitination,Zinc-finger
Research Areas (Faceted)
cell_biology,cell_cycle,transcription_translation,genetics
Species
human
Target Sentence
Ring finger protein 2 (RNF2) is a polycomb group (PcG) protein. RNF2 has been shown to interact with, and suppress the activity of, transcription factor CP2 (TFCP2/CP2). Studies of the mouse counterpart suggest the involvement of this gene in the specification of anterior-posterior axis, as well as in cell proliferation in early development. This protein has also been found to interact with huntingtin interacting protein 2 (HIP2), an ubiquitin-conjugating enzyme, and possess ubiquitin ligase activity [taken from NCBI Entrez Gene (Gene ID: 6045)].
UniGene ID
Hs.591490
UniProt ID (eCommerce)
Q99496

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.