human RNF128 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human RNF128.
shADV-221344
Ad-h-RNF128-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human RNF128 (ring finger protein 128, E3 ubiquitin protein ligase). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
GRAIL
Description (Vector)
RNF128 is a type I transmembrane protein that localizes to the endocytic pathway. This protein contains a RING zinc-finger motif and has been shown to possess E3 ubiquitin ligase activity. Expression of this gene in retrovirally transduced T cell hybridoma significantly inhibits activation-induced IL2 and IL4 cytokine production. Induced expression of this gene was observed in anergic CD4(+) T cells, which suggested a role in the induction of anergic phenotype. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
Gene ID
79589
Gene Name (Vector)
ring finger protein 128, E3 ubiquitin protein ligase
Gene Symbol
RNF128
HGNC ID
HGNC:21153
ORF Size (aa)
1287
ORF Size (bp)
1287 bp
RefSeq ID
NM_024539
RefSeq Synonyms
NM_194463, NM_024539, BC063404,
Species
human
UniGene ID
Hs.496542
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.