human RGS6 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human RGS6.
shADV-221131
Ad-h-RGS6-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human RGS6 (regulator of G-protein signaling 6). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
GAP; HA117; S914
Description (Vector)
RGS6 encodes a member of the RGS (regulator of G protein signaling) family of proteins, which are defined by the presence of a RGS domain that confers the GTPase-activating activity of these proteins toward certain G alpha subunits. This protein also belongs to a subfamily of RGS proteins characterized by the presence of DEP and GGL domains, the latter a G beta 5-interacting domain. The RGS proteins negatively regulate G protein signaling, and may modulate neuronal, cardiovascular, lymphocytic activities, and cancer risk. Many alternatively spliced transcript variants encoding different isoforms with long or short N-terminal domains, complete or incomplete GGL domains, and distinct C-terminal domains, have been described for this gene, however, the full-length nature of some of these variants is not known.
Gene ID
9628
Gene Name (Vector)
regulator of G-protein signaling 6
Gene Symbol
RGS6
HGNC ID
HGNC:10002
ORF Size (aa)
1419
ORF Size (bp)
1419 bp
RefSeq ID
NM_004296
RefSeq Synonyms
NM_004296, NM_001204424, NM_001204423, NM_001204422, NM_001204421, NM_001204420, NM_001204419, NM_001204418, NM_001204417, NM_001204416, BC113572, BC104877,
Species
human
UniGene ID
Hs.509872
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.