human RFXANK shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human RFXANK.
shADV-221077
Ad-h-RFXANK-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human RFXANK (regulatory factor X associated ankyrin containing protein). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ANKRA1; BLS; F14150_1; RFX-B
Description (Vector)
Major histocompatibility (MHC) class II molecules are transmembrane proteins that have a central role in development and control of the immune system. The protein encoded by this gene, along with regulatory factor X-associated protein and regulatory factor-5, forms a complex that binds to the X box motif of certain MHC class II gene promoters and activates their transcription. Once bound to the promoter, this complex associates with the non-DNA-binding factor MHC class II transactivator, which controls the cell type specificity and inducibility of MHC class II gene expression. This protein contains ankyrin repeats involved in protein-protein interactions. Mutations in this gene have been linked to bare lymphocyte syndrome type II, complementation group B. Two transcript variants encoding different isoforms have been described for this gene, with only one isoform showing activation activity.
Gene ID
8625
Gene Name (Vector)
regulatory factor X associated ankyrin containing protein
Gene Symbol
RFXANK
HGNC ID
HGNC:9987
ORF Size (aa)
783
RefSeq ID
NM_003721
RefSeq Synonyms
NM_134440, NM_003721, NM_001278728, NM_001278727, BC114563, BC114558,
Species
human
UniGene ID
Hs.296776
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.