human RAE1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human RAE1.
shADV-220661
Ad-h-RAE1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human RAE1 (ribonucleic acid export 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
dJ481F12.3; dJ800J21.1; MIG14; Mnrp41; MRNP41
Description (Vector)
Mutations in the Schizosaccharomyces pombe Rae1 and Saccharomyces cerevisiae Gle2 genes have been shown to result in accumulation of poly(A)-containing mRNA in the nucleus, suggesting that the encoded proteins are involved in RNA export. The protein encoded by this gene is a homolog of yeast Rae1. It contains four WD40 motifs, and has been shown to localize to distinct foci in the nucleoplasm, to the nuclear rim, and to meshwork-like structures throughout the cytoplasm. This gene is thought to be involved in nucleocytoplasmic transport, and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton. Alternatively spliced transcript variants encoding the same protein have been found for this gene.
Gene ID
8480
Gene Name (Vector)
ribonucleic acid export 1
Gene Symbol
RAE1
HGNC ID
HGNC:9828
ORF Size (aa)
1107
ORF Size (bp)
1107 bp
RefSeq ID
NM_003610
RefSeq Synonyms
NM_003610, NM_001015885, BC106924, BC106923, BC103754,
Species
human
UniGene ID
Hs.371698
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.