human RABEP1 shRNA silencing Adenovirus

Name
Ad-h-RABEP1-shRNA

Cat No
shADV-220599

Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human RABEP1.

shADV-220599

Ad-h-RABEP1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human RABEP1 (rabaptin, RAB GTPase binding effector protein 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

90

shRNA Validated

Yes

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

neurocrescin; rab GTPase-binding effector protein 1; RAB5EP; rabaptin-4; rabaptin-5; rabaptin-5alpha; RABPT5; renal carcinoma antigen NY-REN-17

Description (eCommerce)

RAB GTPase binding effector protein 1 (RABEP1) is a Rab effector protein and acts as a linker between gamma-adaptin, RAB4A and RAB5A. It stimulates RABGEF1 mediated nucleotide exchange on RAB5A RABEP1 and is involved in endocytic membrane fusion and membrane trafficking of recycling endosomes [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q15276].

Gene ID

9135

Gene Name (eCommerce)

rabaptin, RAB GTPase binding effector protein 1

Gene Name (Vector)

rabaptin, RAB GTPase binding effector protein 1

Gene Symbol

RABEP1

HGNC ID

HGNC:17677

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

2589

ORF Size (bp)

2589 bp

Protein Name (eCommerce)

Rab GTPase-binding effector protein 1

RefSeq ID

NM_004703

RefSeq Synonyms

NM_004703, NM_001291582, NM_001291581, NM_001083585, BC041700,

Research Areas

Apoptosis,Transport

Research Areas (Faceted)

cell_biology

Species

human

Target Sentence

RAB GTPase binding effector protein 1 (RABEP1) is a Rab effector protein and acts as a linker between gamma-adaptin, RAB4A and RAB5A. It stimulates RABGEF1 mediated nucleotide exchange on RAB5A RABEP1 and is involved in endocytic membrane fusion and membrane trafficking of recycling endosomes [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q15276].

UniGene ID

Hs.592121

UniProt ID (eCommerce)

Q15276

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.