human PTH1R shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human PTH1R.
shADV-220262
Ad-h-PTH1R-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human PTH1R (parathyroid hormone 1 receptor). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
PFE; PTHR; PTHR1
Description (Vector)
PTH1R is a member of the G-protein coupled receptor family 2. This protein is a receptor for parathyroid hormone (PTH) and for parathyroid hormone-like hormone (PTHLH). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Defects in this receptor are known to be the cause of Jansen's metaphyseal chondrodysplasia (JMC), chondrodysplasia Blomstrand type (BOCD), as well as enchodromatosis. Two transcript variants encoding the same protein have been found for this gene.
Gene ID
5745
Gene Name (Vector)
parathyroid hormone 1 receptor
Gene Symbol
PTH1R
HGNC ID
HGNC:9608
ORF Size (aa)
1782
ORF Size (bp)
1782 bp
RefSeq ID
NM_000316
RefSeq Synonyms
NM_001184744, NM_000316, BC112247, BC112221, BC110388, BC031578,
Species
human
UniGene ID
Hs.1019
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.