human PTGES shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human PTGES.
shADV-220244
Ad-h-PTGES-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human PTGES (prostaglandin E synthase). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
MGST-IV; MGST1-L1; MGST1L1; MPGES; mPGES-1; PGES; PIG12; PP102; PP1294; TP53I12
Description (Vector)
PTGES is a glutathione-dependent prostaglandin E synthase. The expression of this gene has been shown to be induced by proinflammatory cytokine interleukin 1 beta (IL1B). Its expression can also be induced by tumor suppressor protein TP53, and may be involved in TP53 induced apoptosis. Knockout studies in mice suggest that this gene may contribute to the pathogenesis of collagen-induced arthritis and mediate acute pain during inflammatory responses.
Gene ID
9536
Gene Name (Vector)
prostaglandin E synthase
Gene Symbol
PTGES
HGNC ID
HGNC:9599
ORF Size (aa)
459
RefSeq ID
NM_004878
RefSeq Synonyms
NM_004878, BC008280,
Species
human
UniGene ID
Hs.146688
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.