human GIMAP5 shRNA silencing Adenovirus

Name
Ad-h-GIMAP5-shRNA

Cat No
shADV-209881

Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Human GIMAP5.

shADV-209881

Ad-h-GIMAP5-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human GIMAP5 (GTPase, IMAP family member 5). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Validated

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

HIMAP3; IAN-5; IAN4; IAN4L1; IAN5; IMAP3; IROD

Description (Vector)

GIMAP5 encodes a protein belonging to the GTP-binding superfamily and to the immuno-associated nucleotide (IAN) subfamily of nucleotide-binding proteins. In humans, the IAN subfamily genes are located in a cluster at 7q36.1. GIMAP5 encodes an antiapoptotic protein that functions in T-cell survival. Polymorphisms in this gene are associated with systemic lupus erythematosus. Read-through transcription exists between this gene and the neighboring upstream GIMAP1 (GTPase, IMAP family member 1) gene.

Gene ID

55340

Gene Name (Vector)

GTPase, IMAP family member 5

Gene Symbol

GIMAP5

HGNC ID

HGNC:18005

ORF Size (aa)

924

ORF Size (bp)

924 bp

RefSeq ID

NM_018384

RefSeq Synonyms

NM_018384, BC011732,

Species

human

UniGene ID

Hs.647079

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.