human FNIP1 shRNA silencing Adenovirus

Name
Ad-h-FNIP1-shRNA

Cat No
shADV-209210

Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human FNIP1.

shADV-209210

Ad-h-FNIP1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human FNIP1 (folliculin interacting protein 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

60

shRNA Validated

Yes

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

folliculin-interacting protein 1

Description (eCommerce)

Folliculin-interacting protein 1 (FNIP1) binds to the tumor suppressor protein folliculin and to AMP-activated protein kinase (AMPK). FNIP1 participates in the regulation of cellular metabolism and nutrient sensing by modulating the AMPK and target of rapamycin signaling pathways. FNIP1 has a closely related paralog that encodes a protein with similar binding activities. Both related proteins also associate with the molecular chaperone heat shock protein-90 (Hsp90) and negatively regulate its ATPase activity and facilitate its association with folliculin [taken from NCBI Entrez Gene (Gene ID: 96459)].

Gene ID

96459

Gene Name (eCommerce)

folliculin interacting protein 1

Gene Name (Vector)

folliculin interacting protein 1

Gene Symbol

FNIP1

HGNC ID

HGNC:29418

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

3498

ORF Size (bp)

3498 bp

Protein Name (eCommerce)

Folliculin-interacting protein 1

RefSeq ID

NM_133372

RefSeq Synonyms

NM_133372, NM_001346114, NM_001346113, NM_001008738, BC172496, BC156495, BC001956,

Research Areas

Cell Biology

Research Areas (Faceted)

cell_biology

Species

human

Target Sentence

Folliculin-interacting protein 1 (FNIP1) binds to the tumor suppressor protein folliculin and to AMP-activated protein kinase (AMPK). FNIP1 participates in the regulation of cellular metabolism and nutrient sensing by modulating the AMPK and target of rapamycin signaling pathways. FNIP1 has a closely related paralog that encodes a protein with similar binding activities. Both related proteins also associate with the molecular chaperone heat shock protein-90 (Hsp90) and negatively regulate its ATPase activity and facilitate its association with folliculin [taken from NCBI Entrez Gene (Gene ID: 96459)].

UniGene ID

Hs.591273

UniProt ID (eCommerce)

Q8TF40

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.