human FGF8 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human FGF8.
shADV-208982
Ad-h-FGF8-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human FGF8 (fibroblast growth factor 8). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AIGF; FGF-8; HBGF-8; HH6; KAL6
Description (Vector)
FGF8 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein is known to be a factor that supports androgen and anchorage independent growth of mammary tumor cells. Overexpression of this gene has been shown to increase tumor growth and angiogensis. The adult expression of this gene is restricted to testes and ovaries. Temporal and spatial pattern of this gene expression suggests its function as an embryonic epithelial factor. Studies of the mouse and chick homologs revealed roles in midbrain and limb development, organogenesis, embryo gastrulation and left-right axis determination. The alternative splicing of this gene results in four transcript variants.
Gene ID
2253
Gene Name (Vector)
fibroblast growth factor 8
Gene Symbol
FGF8
HGNC ID
HGNC:3686
ORF Size (aa)
735
ORF Size (bp)
735 bp
RefSeq ID
NM_006119
RefSeq Synonyms
NM_033165, NM_033164, NM_033163, NM_006119, NM_001206389, BC128236, BC128235, BC069106,
Species
human
UniGene ID
Hs.57710
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.