human FBXO22 shRNA silencing Adenovirus

Name
Ad-h-FBXO22-shRNA

Cat No
shADV-208789

Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human FBXO22.

shADV-208789

Ad-h-FBXO22-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human FBXO22 (F-box protein 22). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

shRNA Validated

Yes

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

FBX22; FISTC1

Description (Vector)

FBXO22 encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and, as a transcriptional target of the tumor protein p53, is thought to be involved in degradation of specific proteins in response to p53 induction. Alternative splicing results in multiple transcript variants.

Gene ID

26263

Gene Name (Vector)

F-box protein 22

Gene Symbol

FBXO22

HGNC ID

HGNC:13593

ORF Size (aa)

900

ORF Size (bp)

900 bp

RefSeq ID

NM_012170

RefSeq Synonyms

NM_147188, NM_012170, BC041691, BC039024, BC032540, BC020204,

Species

human

UniGene ID

Hs.591115

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.