human FAM12B shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human EDDM3B.
shADV-208388
Ad-h-FAM12B-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human EDDM3B (epididymal protein 3B). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
EP3B; FAM12B; HE3-BETA; HE3B; RAM2
Description (Vector)
Testicular sperm are morphologically differentiated but are not progressively motile nor able to fertilize an egg. Post-testicular maturation requires exposure of spermatozoa to the microenvironment of the epididymal lumen. Spermatozoa undergo extensive changes in the epididymis, including enzymatic modifications, loss of pre-existing components and addition of new glycoproteins from epididymal secretions. These modifying proteins and enzymes are synthesized by epithelial cells lining the epididymal duct and secreted apically into the lumen, where they come into contact with, and may be absorbed onto, the sperm membranes. The proteins encoded by the genes in this cluster are synthesized and secreted by epididymal epithelial cells.
Gene ID
64184
Gene Name (Vector)
epididymal protein 3B
Gene Symbol
EDDM3B
HGNC ID
HGNC:19223
ORF Size (aa)
444
RefSeq ID
NM_022360
RefSeq Synonyms
NM_022360, BC128030,
Species
human
UniGene ID
Hs.525202
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.