human F2 shRNA silencing Adenovirus

Name 
Ad-h-F2-shRNA
Cat No 
shADV-208221
Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Human F2.

shADV-208221
Ad-h-F2-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human F2 (coagulation factor II, thrombin). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
PT; RPRGL2; THPH1
Description (Vector)
Coagulation factor II is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Mutations in F2 leads to various forms of thrombosis and dysprothrombinemia.
Gene ID
2147
Gene Name (Vector)
coagulation factor II, thrombin
Gene Symbol
F2
HGNC ID
HGNC:3535
ORF Size (aa)
1869
ORF Size (bp)
1869 bp
RefSeq ID
NM_000506
RefSeq Synonyms
NM_001311257, NM_000506, BC051332,
Species
human
UniGene ID
Hs.655207

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.