human EPN2 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human EPN2.
shADV-208012
Ad-h-EPN2-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human EPN2 (epsin 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
EHB21; Eps15 binding protein; EPS-15-interacting protein 2; epsin-2
Description (eCommerce)
EPS-15-interacting protein 2 (EPN2) interacts with clathrin and adaptor-related protein complex 2, alpha 1 subunit. EPN2 is found in a brain-derived clathrin-coated vesicle fraction and localizes to the peri-Golgi region and the cell periphery. The protein is thought to be involved in clathrin-mediated endocytosis [taken from NCBI Entrez Gene (Gene ID: 22905)].
Description (Vector)
EPN2 encodes a protein which interacts with clathrin and adaptor-related protein complex 2, alpha 1 subunit. The protein is found in a brain-derived clathrin-coated vesicle fraction and localizes to the peri-Golgi region and the cell periphery. The protein is thought to be involved in clathrin-mediated endocytosis. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms.
Gene ID
22905
Gene Name (eCommerce)
epsin 2
Gene Name (Vector)
epsin 2
Gene Symbol
EPN2
HGNC ID
HGNC:18639
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1755
ORF Size (bp)
1755 bp
Protein Name (eCommerce)
Epsin-2
RefSeq ID
NM_148921
RefSeq Synonyms
NM_148921, NM_014964, NM_001102664, BC093974, BC093972,
Research Areas
EGFR Signaling,Notch Signaling,Signal Transduction
Research Areas (Faceted)
signal_transduction,developmental_biology
Species
human
Target Sentence
EPS-15-interacting protein 2 (EPN2) interacts with clathrin and adaptor-related protein complex 2, alpha 1 subunit. EPN2 is found in a brain-derived clathrin-coated vesicle fraction and localizes to the peri-Golgi region and the cell periphery. The protein is thought to be involved in clathrin-mediated endocytosis [taken from NCBI Entrez Gene (Gene ID: 22905)].
UniGene ID
Hs.715517
UniProt ID (eCommerce)
O95208
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.