human EML1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human EML1.
shADV-207883
Ad-h-EML1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human EML1 (echinoderm microtubule associated protein like 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
BH; ELP79; EMAP; EMAPL; HuEMAP
Description (Vector)
Human echinoderm microtubule-associated protein-like is a strong candidate for the Usher syndrome type 1A gene. Usher syndromes (USHs) are a group of genetic disorders consisting of congenital deafness, retinitis pigmentosa, and vestibular dysfunction of variable onset and severity depending on the genetic type. The disease process in USHs involves the entire brain and is not limited to the posterior fossa or auditory and visual systems. The USHs are catagorized as type I (USH1A, USH1B, USH1C, USH1D, USH1E and USH1F), type II (USH2A and USH2B) and type III (USH3). The type I is the most severe form. Gene loci responsible for these three types are all mapped. Two transcript variants encoding different isoforms have been found for this gene.
Gene ID
2009
Gene Name (Vector)
echinoderm microtubule associated protein like 1
Gene Symbol
EML1
HGNC ID
HGNC:3330
ORF Size (aa)
2448
ORF Size (bp)
2448 bp
RefSeq ID
NM_004434
RefSeq Synonyms
NM_004434, NM_001008707, BC033043, BC032541,
Species
human
UniGene ID
Hs.12451
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.