human EIF3J shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human EIF3J.
shADV-207757
Ad-h-EIF3J-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human EIF3J (eukaryotic translation initiation factor 3 subunit J). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
eIF3 p35; eIF-3-alpha; eIF3-alpha; eIF3j; eIF3-p35; EIF3S1; Eukaryotic translation initiation factor 3 subunit 1; eukaryotic translation initiation factor 3 subunit J; eukaryotic translation initiation factor 3, subunit 1 (alpha, 35kD)
Description (eCommerce)
Eukaryotic initiation factor 3 subunit J (eIF3J) is one of at least 13 non-identical protein subunits of eukaryotic initiation factor 3 (eIF3). eIF3 is the largest eIF (~650 kDa) and functions to facilitate binding of the 40S ribosomal subunit to the 5’-end of cellular mRNAs near the cap structure (m7GpppN). eIF3J is proposed to act as a factor that further stabilizes the interaction between eIF3 and the ribosome.
Description (Vector)
Eukaryotic initiation factor-3 (EIF3) has a molecular mass of about 600 kD and contains 13 nonidentical protein subunits, including EIF3J. EIF3 plays a central role in binding of initiator methionyl-tRNA and mRNA to the 40S ribosomal subunit to form the 40S initiation complex (Fraser et al., 2004 (PubMed 14688252); Fraser et al., 2007 (PubMed 17588516)).(supplied by OMIM, Mar 2008)
Gene ID
8669
Gene Name (eCommerce)
eukaryotic translation initiation factor 3 subunit J
Gene Name (Vector)
eukaryotic translation initiation factor 3 subunit J
Gene Symbol
EIF3J
HGNC ID
HGNC:3270
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
777
ORF Size (bp)
777 bp
Protein Name (eCommerce)
Eukaryotic translation initiation factor 3 subunit J
RefSeq ID
NM_003758
RefSeq Synonyms
NM_003758, NM_001284336, NM_001284335, BC002719,
Research Areas
Gene Expression,Metabolism/Metabolic Process,mRNA Binding,RNA Transport,Translational Control
Research Areas (Faceted)
genetics,transcription_translation,metabolism,cell_biology
Species
human
Target Sentence
Eukaryotic initiation factor 3 subunit J (eIF3J) is one of at least 13 non-identical protein subunits of eukaryotic initiation factor 3 (eIF3). eIF3 is the largest eIF (~650 kDa) and functions to facilitate binding of the 40S ribosomal subunit to the 5’-end of cellular mRNAs near the cap structure (m7GpppN). eIF3J is proposed to act as a factor that further stabilizes the interaction between eIF3 and the ribosome.
UniGene ID
Hs.404056
UniProt ID (eCommerce)
O75822
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.