mouse RSPO3 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Rspo3.
shAAV-271188
AAV-m-RSPO3-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Rspo3 (R-spondin 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
2810459H04Rik; AW742308; Cristin1; Thsd2
Description (Vector)
Activator of the beta-catenin signaling cascade, leading to TCF-dependent gene activation. Acts both in the canonical Wnt/beta-catenin-dependent pathway and in non-canonical Wnt signaling pathway, probably by acting as an inhibitor of ZNRF3, an important regulator of the Wnt signaling pathway. Acts as a ligand for frizzled FZD8 and LRP6. May negatively regulate the TGF-beta pathway (By similarity).
Gene ID
72780
Gene Name (Vector)
R-spondin 3
Gene Symbol
Rspo3
ORF Size (aa)
834
ORF Size (bp)
834 bp
RefSeq ID
NM_028351
RefSeq Synonyms
NM_028351, BC145931, BC145929, BC103794,
Species
mouse
UniGene ID
Mm.45191
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.