mouse RNF6 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Rnf6.
shAAV-270754
AAV-m-RNF6-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Rnf6 (ring finger protein (C3H2C3 type) 6). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
1200013I08Rik; 5730419H05Rik; AA537053
Description (Vector)
E3 ubiquitin-protein ligase mediating 'Lys-48'-linked polyubiquitination of LIMK1 and its subsequent targeting to the proteasome for degradation. Negatively regulates axonal outgrowth through regulation of the LIMK1 turnover. Mediates 'Lys-6' and 'Lys-27'-linked polyubiquitination of AR/androgen receptor thereby modulating its transcriptional activity. May also bind DNA and function as a transcriptional regulator.
Gene ID
74132
Gene Name (Vector)
ring finger protein (C3H2C3 type) 6
Gene Symbol
Rnf6
ORF Size (aa)
2004
ORF Size (bp)
2004 bp
RefSeq ID
NM_028774
RefSeq Synonyms
NM_028774, NM_001256087, NM_001256086, NM_001256085, BC138545,
Species
mouse
UniGene ID
Mm.26696
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.