mouse FKBP4 shRNA silencing AAV

Name
AAV-m-FKBP4-shRNA

Cat No
shAAV-259452

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Mouse Fkbp4.

shAAV-259452

AAV-m-FKBP4-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Fkbp4 (FK506 binding protein 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

59kDa; AL022792; AW208983; FKBP-4; FKBP-52; FKBP52; FKPB52; p59

Description (Vector)

Immunophilin protein with PPIase and co-chaperone activities (By similarity). Component of unligated steroid receptors heterocomplexes through interaction with heat-shock protein 90 (HSP90). May play a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors between cytoplasm and nuclear compartments (By similarity). The isomerase activity controls neuronal growth cones via regulation of TRPC1 channel opening. Acts also as a regulator of microtubule dynamics by inhibiting MAPT/TAU ability to promote microtubule assembly.

Gene ID

14228

Gene Name (Vector)

FK506 binding protein 4

Gene Symbol

Fkbp4

ORF Size (aa)

1377

ORF Size (bp)

1377 bp

RefSeq ID

NM_010219

RefSeq Synonyms

NM_010219, BC003447,

Species

mouse

UniGene ID

Mm.12758

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.