mouse FAM120A shRNA silencing AAV

Name 
AAV-m-FAM120A-shRNA
Cat No 
shAAV-258936
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Fam120a.

shAAV-258936
AAV-m-FAM120A-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Fam120a (family with sequence similarity 120, member A). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
C9orf10; Ossa
Description (Vector)
FAM120A may participate in mRNA transport in the cytoplasm (By similarity). Critical component of the oxidative stress-induced survival signaling. Activates src family kinases and acts as a scaffolding protein enabling src family kinases to phosphorylate and activate PI3-kinase. Binds RNA and promotes the secretion of IGF-II. May play a pivotal role in the progression of scirrhous-type gastric cancer by supporting cancer cell survival in environments with various oxidative stresses.
Gene ID
218236
Gene Name (Vector)
family with sequence similarity 120, member A
Gene Symbol
Fam120a
ORF Size (aa)
3339
ORF Size (bp)
3339 bp
RefSeq ID
NM_001033268
RefSeq Synonyms
NM_001033268, BC167198,
Species
mouse
UniGene ID
Mm.426571

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.